To live, to err, to fall, to triumph, to recreate life out of life. —James Joyce what's cooking now Single-cell Metabolic Profiling We develop chemical methods for quantifying metabolites and proteins at the single-cell level. Single-cell Signaling Dynamics We establish non-genetic approaches to interrogate cell signaling activities with single-cell resolution. Nanotein We construct multi-cyclic peptides for modulating protein-protein interactions. Endocytosis Promoting Peptides We explore drug delivery applications of cyclic peptides.