PUBLICATIONS

25. MYC-targeting inhibitors generated from a stereodiversified bicyclic peptide library
Z. Li, Y. Huang, T-I Hung, J. Sun, D. Aispuro, B. Chen, N. Guevara, F. Ji, X. Cong, L. Zhu, S. Wang, Z. Guo, C. Chang, and M. Xue
J. Am. Chem. Soc. 2024, 146, 1356. doi.org/10.1021/jacs.3c09615

24. Multiplex protein imaging through PACIFIC: photoactive immunofluorescence with iterative cleavage
F. Ji, M. Hur, S. Hur, S. Wang, P. Sarkar, S. Shao, D. Aispuro, X. Cong, Y. Hu, Z. Li, and M. Xue
ACS Bio Med Chem Au 2023, 3, 283. doi.org/10.1021/acsbiomedchemau.3c00018
(Featured as journal cover)

23. Label-free analysis of binding and inhibition of SARS-Cov-19 spike proteins to ACE2 receptor with ACE2-derived peptides by surface plasmon resonance
F. Abouhajar, R. Chaudhuri, S. N. Valiulis, D. D. Stuart, A. S. Malinick, M. Xue, and Q. Cheng
ACS Appl. Bio Mater 2023, 6, 182. doi.org/10.1021/acsabm.2c00832

22. Hydroxyl-rich hydrophilic endocytosis-promoting peptide with no positive charge
S. Wang, Z. Li, D. Aispuro, N. Guevara, J. V. Valkenburgh, B. Chen, X. Zhou, M. N. McCarroll, F. Ji, X. Cong,
P. Sarkar, R. Chaudhuri, Z. Guo, N. P. Perkins, S. Shao, J. K. Sello, K. Chen, and M. Xue
J. Am. Chem. Soc. 2022, 144, 20288. doi.org/10.1021/jacs.2c07420
(Featured in S. Greed, Nat. Rev. Chem, 2022, 6, 841.)

21. Digitonin-facilitated delivery of imaging probes enables single-cell analysis of AKT signaling activities in suspension cells
S. Wang, N.G. Perkins, F. Ji, R. Chaudhuri, Z. Guo, P. Sarkar, S. Shao, Z. Li, and M. Xue
Analyst 2021, 146, 5307. doi: 10.1039/D1AN00751C

20. Single-cell profiling of fatty acid uptake using surface-immobilized dendrimers
Z. Guo, H. Cheng, Z. Li, S. Shao, P. Sarkar, S. Wang, R. Chaudhuri, N.G. Perkins, F. Ji, W. Wei, and M. Xue
J. Am. Chem. Soc. 2021, 143, 11191. doi: 10.1021/jacs.1c05103

19. Real-time analysis of AKT signaling activities at single-cell resolution using cyclic peptide-based probes
F. Ji, S. Wang, S. Shao, P. Sarkar and M. Xue
Methods Mol. Biol. 2021, in press.

18. Single-cell profiling of D-2-hydroxyglutarate using surface-immobilized resazurin analogs
H. Cheng, Z. Li, Z. Guo, S. Shao, L. Mo, W. Wei, and M. Xue
Biosens. Bioelectron. 2021, 190, 113368. doi: 10.1016/j.bios.2021.113368

17. Hexokinase 2 discerns a novel circulating tumor cell population associated with poor prognosis in lung cancer patients
L. Yang, X. Yan, J. Chen, Q. Zhan, Y. Hua, S. Xu, Z. Li, Z. Wang, Y. Dong, D. Zuo, M. Xue, Y. Tang, H.R. Herschman, S. Lu,
Q. Shi, and W. Wei
Proc. Natl. Acad. Sci. U.S.A. 2021, 118, e2012228118. doi: 10.1073/pnas.2012228118

16. Chemical sensors for biomedical use
X. Xie, D. Citterio, K. Chumbimuni-Torres, M. Xue, and X. Wang
Front. Chem. 2021, 9, 283. doi: 10.3389/fchem.2021.685563 (Editorial)

15. A cyclic peptide antenna ligand for enhancing terbium luminescence
F. Ji, S. Shao, Z. Li, S. Wang, R. Chaudhuri, Z. Guo, N.G. Perkins, P. Sarkar, and M. Xue
Analyst 2021, 146, 3474-3481. doi: 10.1039/D1AN00530H (Featured as journal cover)

14. Inhibiting matrix metalloproteinase-2 activation by perturbing protein-protein interactions using a cyclic peptide
P. Sarkar, Z. Li, W. Ren, S. Wang, S. Shao, J. Sun, X. Ren, N.G. Perkins, Z. Guo, C.-E. A. Chang, J. Song, and M. Xue
J. Med. Chem. 2020, 63, 6979-6990. doi: 10.1021/acs.jmedchem.0c00180 (Featured as journal cover)

13. Multi-omic single-cell snapshots reveal multiple independent trajectories to drug tolerance in a melanoma cell line
Y. Su, M.E. Ko, H. Cheng, R. Zhu, M. Xue, J. Wang, J.W. Lee, L. Frankiw, A. Xu, S. Wong, L. Robert, K. Takata, D. Yuan,
Y. Lu, S. Huang, A. Ribas, R. Levine, G.P. Nolan, W. Wei, S.K. Plevritis, G. Li, D. Baltimore, and J.R. Heath
Nat. Comm. 2020, 11, 2345. doi: 10.1038/s41467-020-15956-9

12. Monitoring the crosstalk between methylation and phosphorylation on histone peptides with host-assisted
capillary electrophoresis
J. Lee, J. Chen, P. Sarkar, M. Xue, R.J. Hooley, and W. Zhong
Anal. Bioanal. Chem. 2020, doi: 10.1007/s00216-020-02486-y

11. Sensing of citrulline modifications in histone peptides by deep cavitand hosts
A.D. Gill, B.L. Hickey, S. Wang, M. Xue, W. Zhong, and R.J. Hooley
Chem. Comm. 2019, 55, 13259-13262. doi: 10.1039/C9CC07002H

10. Liquid biopsy-based single-cell metabolic phenotyping of lung cancer patients for informative diagnostics
Z. Li, Z. Wang, Y. Tang, X. Lu, J. Chen, Y. Dong, B. Wu, C. Wang, L. Yang, Z. Guo, M. Xue, S. Lu, W. Wei, and Q. Shi
Nat. Comm. 2019, 10 (1): 1856. doi: 10.1038/s41467-019-11808-3

9. Fluorescence imaging-based methods for single-cell protein analysis
S. Wang, F. Ji, Z. Li, and M. Xue, Anal. Bioanal. Chem. 2019, 3, 1-9. doi: 10.1007/s00216-019-01694-5

8. A chemical approach for profiling intracellular AKT signaling dynamics from single cells
S. Shao, Z. Li, H. Cheng, S. Wang, N.G. Perkins, P. Sarkar, W. Wei, and M. Xue
J. Am. Chem. Soc. 2018, 140, 13586-13589. doi: 10.1021/jacs.8b08931

7. Construction of a sequenceable protein mimetic peptide library with a true 3D-diversifiable chemical space
Z. Li, S. Shao, X. Ren, J. Sun, Z. Guo, S. Wang, M.M. Song, C.-E.A. Chang, and M. Xue
J. Am. Chem. Soc. 2018, 140, 14552-14556. doi: 10.1021/jacs.8b08338

6. Design of a multispherical cavity carbon with in situ silica modifications and its self‐humidification application on
fuel cell anode support
J. Zhang, D. Liu, S. Hou, L. Du, H. Song, S. Liao, and M. Xue
Adv. Mater. Inter. 2018, 5, 1800314. doi: 10.1002/admi.201800314

5. Surface immobilization of redox‐labile fluorescent probes: enabling single‐cell co‐profiling of aerobic glycolysis and
oncogenic protein signaling activities
Z. Li, H. Cheng, S. Shao, X. Lu, L. Mo, J. Tsang, P. Zeng, Z. Guo, S. Wang, D. A. Nathanson, J. R. Heath, W. Wei, M. Xue
Angew. Chem. Int. Ed. 2018, 57, 11554-11558. doi: 10.1002/anie.201803034

4. An efficient carbon catalyst supports with mesoporous graphene-like morphology
D. Liu, J. Zhang, C. Zhang, M. Lv, X. Zhang, H. Song, L. Du, and M. Xue,
J. Porous Mater. 2018, 25, 913-921.doi: 10.1007/s10934-017-0503-1

3. Supramolecular analytical chemistry in cancer research
S. Shao and M. Xue, Adv. Cancer Res. 2018, 139, 147-161. doi: 10.1016/bs.acr.2018.04.005

2. Single-cell analysis resolves the cell state transition and signaling dynamics associated with melanoma drug-induced resistance
Y. Su, W. Wei, L. Robert, M. Xue, J. Tsoi, A. Garcie-Diaz, B.H. Moreno, J. Kim, R.H. Ng, J.W. Lee, R.C. Koya, B. Comin-Anduix,
T.G. Graeber, A. Ribas, and J.R. Heath,
Proc. Natl. Acad. Sci. U.S.A. 2017, 114, 13679-13684. doi: 10.1073/pnas.1712064115

1. Single-cell phosphoproteomics resolves adaptive signaling dynamics and informs targeted combination therapy in glioblastoma
W. Wei, Y.S. Shin, M. Xue, T. Matsutani, K. Masui, H. Yang, Y. Gu, H. Ken, X. Ding, K. Hwang, J. Kim, J. Zhou, X. Li,
B. Bonetti, R. Chopra, C.D. James, W.K. Cavenee, T.F. Cloughesy, P.S. Mischel, J.R. Heath, and B. Gini,
Cancer Cell, 2016, 29, 563-573. doi: 10.1016/j.ccell.2016.03.012